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AP Photo/Al Behrman

25. Duke upsets UNLV

Duke beating anyone in the NCAA tournament is rarely considered an upset, but that was certainly the case after the No. 6 Blue Devils topped No. 1 seed UNLV in a 1991 semifinal in Indianapolis. The Runnin' Rebels entered the game with a 34-0 record and had won 45 straight overall. Two free throws by Christian Laettner with 12 seconds remaining gave Duke a 79-77 lead. The game was over when Anderson Hunt missed a 3-point attempt at the buzzer. Two days later, Duke defeated Kansas to win the NCAA title. -- Jason King