Touted freshman center Adam Woodbury scored 10 points in his college debut for the Hawkeyes, who opened the game with a 17-2 lead.
The Broncs cut Iowa's early lead to 33-22 with 2:52 left in the first half, but the Hawkeyes ended the half on a 12-2 run. Iowa cruised in the second half.
Devyn Marble, Iowa's leading returning scorer, had 10 points.
Friday's attendance of 14,859 fans was Iowa's largest for a season opener since 2001.
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Sebastien Bellin's friend Chris Young joins Ryan Smith on Outside the Lines to discuss his friend's bravery, courage and strength after surviving the Brussels bombings in March.
Andrew White III is leaving the Nebraska men's basketball team and will play elsewhere for his final college season.
A cameraman fell down trying to film Ben Simmons at the NBA Draft. Flashing back to his LSU days proves this is nothing new.