Horton had 22 points, 10 rebounds and seven blocked shots, all career highs. Blackwood added 26 points and seven assists for the Blue Devils (6-10, 2-3 Northeast Conference).
Cale Nelson led the Red Flash (3-12, 1-3) with 20 points and had the visitors ahead early. Nelson scored his team's first seven points for a 7-2 lead.
But Blackwood's 3-point play and his assist to Horton for a layup capped a 13-2 run and Central was up 15-9 and never relinquished the lead. The Blue Devils had a 45-29 lead at the break.
The Red Flash pared the lead to late in the second half but Blackwood scored seven straight points and the Blue Devils would cruise the rest of the way.
Guard Naz Mitrou-Long, whose 2015-16 season ended in December due to hip problems, has been granted a hardship waiver for the coming season, Iowa State said.
As the Sooners look to life without superstar Buddy Hield and his sidekicks, it's clear their unseasoned players will need to grow up fast.
The Central Intercollegiate Athletic Association says it won't move its headquarters, its basketball tournament or other conference championships from North Carolina, despite