It was the third straight game in which Vasquez reached the 20-point mark. The senior guard went 12-for-20 from the field, had eight rebounds and five assists to help Maryland (8-3) to its fourth win in five games.
The Terrapins played without second-leading scorer Sean Mosley, who has a sprained left ankle. The sophomore forward participated in warmups and dressed for the game but did not see action for the first time in his career.
Maryland limited the Owls to 30 percent shooting and forced 11 turnovers to lead 39-27 at halftime.