It was the third straight win for the Eagles (9-4) after embarrassing home losses to Harvard and Rhode Island -- both teams from weaker conferences.
Biko Paris added 14 points, with four coming on free throws in the closing minute, for Boston College.
The Gamecocks lost their third game to an Atlantic Coast Conference team this season. They also were beaten by Miami and Clemson.
South Carolina, which trailed 48-27 at halftime, quickly got back into the game by forcing turnovers and frustrating the Eagles' offense with a fullcourt press.
After a season that saw his shooting numbers slip, should Nigel Hayes return for his senior year at Wisconsin or take the gamble to put him name in this year's NBA draft?
Isaiah Taylor talks about his decision to declare for the NBA draft and what he will miss most about Texas.
Chattanooga women's basketball coach Jim Foster has received a one-year contract extension, the same day the school gave the men's coach a two-year extension.