Cade Davis scored 21 points to lead Oklahoma (12-17, 4-11), which shot just 32.8 percent from the field, hitting 21 of 64 shots.
Texas Tech outrebounded Oklahoma 46-37 but had more turnovers, 16, than the Sooners' 12. But Oklahoma got just 11 points off the turnovers, while Texas Tech scored 21 points off Sooners' turnovers.
The game got sloppy at times, leading to eight steals for each team.
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