Terrell Vinson added 18 points and Sean Carter 15 for the Minutemen (13-4, 2-1 Atlantic-10 Conference), who have won seven of their last eight games. UMass got back on track after having its season-high six-game losing snapped the last time out, 82-75 on Sunday at La Salle.
UMass opened the game on a 12-2 run and never looked back, leading for the entire contest. The Minutemen led by 11 points at halftime and held on despite being edged 42-41 in the second half by the 49ers.
Putney, whose scoring output was a career high, also pulled down a game-high 10 rebounds for UMass, which outrebounded Charlotte 36-25.
Chris Braswell scored 31 points to pace the 49ers (9-6, 2-1).
Which venue in the Mountain West is the toughest place to steal a win? Cast your vote.
Who can challenge DeAndre Ayton for No. 1 in the ESPN 100? It's one of the issues worth watching as we exit basketball recruiting's biggest month.
Five-star guard Coby White only needed three days to accept an offer from head coach Roy Williams. White, No. 21 in the ESPN 60 committed to the North Carolina Thursday.