After the Cougars (4-2) led 66-52 with 5:34 to play, the Buccaneers (2-4) reeled off 12 consecutive points. Saah Nimley and Arlon Harper, who finished with 20 points apiece, scored 10 of the Bucs' points in that run.
Harper buried a 3-pointer to make it a one-point game, 68-67, with 41 seconds left after Lawrence hit two free throws for the Cougars. Harper was unsuccessful on his next two 3-point tries, however, as Lawrence secured the game for College of Charleston with four free throws in the final 31 seconds.
The teams played at Charleston Southern's 881-seat Buccaneer Field House for the first time since 1992. Games hosted by Charleston Southern in the rivalry since then were played at the larger North Charleston Coliseum.
Purdue coach Matt Painter says players haven't used the fifth-year graduate transfer rule for its true intent.
The dust has settled after players made their NBA draft decisions. Which college teams won? Which lost? Well, Villanova is pretty happy. USC, meanwhile, might not be as thrilled.
The 2017 recruiting class is short on point guards, with Trevon Duval leading only eight prospects from the ESPN 60 who are still available.