Clark scored from the left block and then finished off a fast break with a finger roll to send Oklahoma (7-2) on a decisive 15-3 run midway through the second half. Osby finished it off with a two-handed dunk off of Steven Pledger's alley-oop to give the Sooners a 56-44 edge with 6:18 remaining.
Elston Turner led Texas A&M (7-2) with 17 points and Ray Turner scored 12. The Aggies matched their season high with 19 turnovers, including on four of five possessions after they'd rallied to tie it at 41. That allowed Oklahoma to take control for good.