Sykes hit 6 of 13 from the field and 10 of 15 at the foul line and added seven rebounds. Spurlock also grabbed seven boards and added a 4-of-7 showing from 3-point range for the Knights (18-9, 8-5).
Tulsa (14-13, 6-7) led 38-35 shortly after halftime, but the Knights used a 7-0 run to take the lead. The Golden Hurricane pulled within 48-45 with 12:36 left, but then Sykes' layup sparked a 12-2 run to build an insurmountable cushion.
Forward Kennedy Meeks, who has averaged 9.4 points and 6.5 rebounds at North Carolina, has pulled out of the NBA draft and will return to the Tar Heels.
Cal big man Ivan Rabb could have been selected in the top 10 of the NBA draft. Instead, he's returning to Berkeley to make himself, and the Golden Bears, stronger.
Devin Williams' decision last month to sign with an agent and enter the NBA draft has left West Virginia in a tough spot.