South Alabama (2-2) had been up by seven late in the game until Brown hit a layup and a three-point play to cut the gap to 53-51 with 6:28 left. The lead went back-and-forth until Watson hit a pair of 3-pointers, the last one converted into a four-point play, putting Southern Mississippi (4-0) up for keeps.
Augustine Rubit led South Alabama with 17. Antoine Allen scored 14, hitting four 3-pointers. Allen's last 3 had pulled the Jaguars within 58-57 with 3:21 remaining. The Jaguars were hampered by 15 turnovers and were cold at the free throw line, making 16 of 25.