Drake (12-9, 3-6 Missouri Valley) raced to a 13-4 lead, fueled by a pair of 3-pointers by Chris Caird. Missouri State (14-7, 4-5) came back to go up 30-29 with 3:13 in the first, but Drake countered to lead 38-35 at the break.
Missouri State went up five on Gavin Thurman's jumper with 7:21 left in the game. Drake coach Ray Giacoletti immediately called time, and his Bulldogs scored 15 of the next 17 points to wrest control of the game.
Drake shot 52 percent from the floor, including 14 of 24 from beyond the arc. Daniels had five 3-pointers, and Caird added 18 points, hitting 6 of 8 3-point attempts.