The Tigers (4-1) held an early three-point lead and closed the half on a 25-11 surge, coasting out to a 40-23 lead at the break.
George Mason (4-2) crawled back throughout the second half as Vaughn Gray hit a layup and Johnny Williams sank two free throws to tie the game at 66 with 1:21 remaining, but Brase answered with a layup.
Sherrod Wright couldn't connect on a jumper, and Bray made a layup with 12 seconds left to cut the Patriots' rally bid short.
Wright paced George Mason with 27 points on 10 of 16 shooting.
Leaving early for the NBA is a risky decision. Some players -- Skal Labissiere, Dejounte Murray -- slid in the draft. Some -- Isaiah Taylor, Troy Williams -- weren't drafted at all.
College basketball coaches across the country will hit the recruiting trail hard in July to target the Class of 2017's top prospects. Which players are the nation's top programs targeting?
The Tar Heels could lose Justin Jackson and Kennedy Meeks after next season. Coach Roy Williams has nearly every top-10 2017 prospect on his board.