After falling behind early, Akron used a 24-2 run through the middle of the first half to build a 35-19 lead at the break. The Zips started slow again in the second, but rolled off 15 straight points to open a 24-4 run which led to their biggest advantage at 66-38.
Kwan Cheatham, Jr. had a career-high 14 points and Reggie McAdams added 11 for Akron (14-6, 6-1 Mid-American) which remains in first place in the MAC East Division.
Majok Majok had 15 points to lead Ball State (4-14, 1-6).
Jesse Berry's layup with 13:12 left in the first gave Ball State its largest lead at 12-6. The Cardinals opened the second half with a 14-2 run to close within 39-33.