Kemp had 11 points in the first half to help East Carolina (2-0) build a 36-24 halftime lead.
Methodist (0-1) struggled from the field, shooting just 31.1 percent (19 of 61) for the game.
East Carolina shot 55.6 percent (20 for 36) and forced Methodist into 10 turnovers in the second half to blow the game open.
The Pirates scored 14 points in the second half off of Methodist turnovers while outscoring the Monarchs 32-10 on points in the paint.
Marshall Guilmette scored nine points and grabbed nine rebounds to lead East Carolina off the bench.
Bryan Hockaday led Methodist with 15 points and 10 rebounds.
Ben Simmons explains what he is focusing on ahead of the start of his NBA career.
After John Calipari's comments about the Louisville scandal, Rick Pitino says that Calipari should not be worried about other programs and to keep quiet unless he is praising another institution.
College basketball coaches across the country will hit the recruiting trail hard in July to target the Class of 2017's top prospects. Which players are the nation's top programs targeting?