It was the Bulls second consecutive win without an offensive touchdown. USF (2-4) is 2-0 in the American Athletic Conference after beating Cincinnati last week.
Kloss' 44-yard field goal with just over 4 minutes left capped a more than 7 minute fourth-quarter drive, and was the game winner. He has converted on nine consecutive attempts, including a 47-yarder in the first half.
Lyle McCombs had a career-high 164 yards rushing and a touchdown for Connecticut, which has lost five straight games to open a season for the first time since 1977. The loss spoiled the debuts of freshman quarterback Tim Boyle, who went 15 of 43 for 149 yards, and interim coach T.J. Weist, who took over the UConn program two weeks ago when Paul Pasqualoni was fired.
The Bulls were playing without injured quarterback Steve Bench and starting running back Marcus Shaw, who had been averaging more than 110 yards a game rushing before suffering a leg injury a week ago. They won despite being outgained 356-228.
The Bulls winning drive went 65 yards in 13 plays. USF just missed out on a touchdown when Steven Bravo-Brown got his hands on a 26-yard pass, but dropped the ball in the end zone.
UConn, which was held scoreless in the second half, got the ball back twice more. They drove to midfield with 6 seconds left, but a Hail Mary on the game's final play fell incomplete in the end zone.
Boyle, who turned 19 last week, got off to a slow first start for the Huskies. He hit his initial throw, a 10-yard completion to wide receiver Geremy Davis, then missed his next seven, including two that would have been touchdowns, but went off the arms of his receivers.
USF's defense then got its third touchdown in three weeks. Ryne Giddins knocked the ball away from Boyle, and Lynch picked up the loose ball and rumbled 44-yards to make it 7-3 late in the first quarter.
It took the Huskies just four plays to retake the lead as McCombs weaved his way for a 52-yard touchdown run, his longest run of the season and longest since 2011.
The junior's previous rushing high this season had been 76 yards. He had 135 in the first half of this one.
Kloss, who hit four field goals last week, capped a six-play second quarter drive to score 10-10. The junior has five field goals of 47 yards or more on the year, a new school record.
Connecticut had a chance to take the lead in the third quarter, but Julius Forte blocked a 47-yard field goal attempt, the second week in a row that South Florida has blocked a kick.
Connecticut's running game came in averaging less than 46 yards a game, but had 207 on Saturday.
But neither team could move the ball, especially in the second half. They combined for 16 punts during the game.
The win gives the Bulls their first 2-0 conference start since 2003, when the program was in Conference USA.
Former Blinn College coach Brad Franchione describes Panthers star Cam Newton's transformation from playing at the junior college in 2009 to playing in Super Bowl 50.
North Carolina inked the No. 34-ranked recruiting class in the 2016 cycle with one ESPN 300 (Tomon Fox) and four more four-stars. The class of 2017 is well on the way to besting the 2016 class with four ESPN Jr300 verbals less than one week after signing day with the most recent being in state receiver Ryan Jones Friday.
Oregon running back Thomas Tyner has decided to take a medical retirement after sitting out all of last season because of a shoulder injury.
It hasn't been an easy road at USC for Pat Haden, the former Trojans quarterback turned athletic director, but at 63, he's earned the right to relax.
Readers want to know about all "downer" material, Iowa cutting ties with Stanford and an inherent southern bias in recruiting rankings.
What did we learn from the Big 12 conference sessions this week? Jake Trotter sorts it out in this edition of the mailbag.