SAN DIEGO -- Conner Hempel threw for 345 yards and four touchdowns as Harvard turned a close game into a runaway, defeating San Diego 42-20 on Saturday.
Defensive end Zach Hodges picked up a Mason Mills fumble and rumbled 53 yards for a touchdown to open the scoring. Paul Stanton Jr. rushed 11 yards for a touchdown in the second quarter and Harvard (1-0) held a one-point lead at half, 14-13.
Hempel took over in the second half, tossing four touchdown passes to three receivers to lead the onslaught.
Mills went 27 of 46 for 293 yards and hooked up with Reggie Bell (7 catches, 101 yards) for a 12-yard fourth quarter touchdown. Mills was intercepted on the next possession leading to Harvard's final touchdown, a 30-yard toss from Hempel to Andrew Fischer -- his second score of the day.
Harvard defeated San Diego (1-2) in its opener for the second consecutive season.
Will Grier threw four touchdown passes to four receivers -- all in the first half -- and No. 25 Florida downed third-ranked Mississippi 38-10 on Saturday night.
Leonard Fournette highlighted his SEC-record third straight 200-yard game with a 75-yard touchdown run, and No. 9 LSU overcame Eastern Michigan 44-22 on Saturday night.
An officiating error led to an Oklahoma State touchdown Saturday in the Cowboys' 36-34 win over Kansas State.
Texas A&M receiver Ricky Seals-Jones, who was ejected for targeting midway in the second quarter of Saturday's game, took to Twitter late in the game, retweeting a tweet that questioned the call.
Florida State running back Dalvin Cook exited in the first quarter of the Seminoles' 24-16 win over Wake Forest with a left hamstring injury. He is day-to-day.
As if things weren't going bad enough at Texas, the Longhorns appear to have players on Twitter during lopsided losses and jabs at their coach accidentally being sent from other nearby teams.