LOS ANGELES -- Although Ed Orgeron claims he isn't a very happy man most mornings, he was ecstatic from the moment he awoke Thursday for his first game as Southern California's interim coach.
"I was just happy to get to represent USC," he said.
That's the attitude Orgeron has spent nearly two weeks attempting to instill in his Trojans, who didn't have much fun during a desultory start to the season under Lane Kiffin.
So far, Orgeron's plan is working well enough to send him to bed in the same marvelous mood.
Cody Kessler passed for 297 yards and two TDs as the revitalized Trojans (4-2, 1-2 Pac-12) survived Arizona's second-half rally to win for the stalwart defensive line coach who replaced the fired Kiffin on Sept. 29. Orgeron set a familial mood from the moment USC entered the Coliseum, gathering the players in a circle at midfield for an emotional pep talk and prayer.
"We love Coach O like a dad," linebacker Hayes Pullard said. "We look up to him. That's a great feeling. That's the bond you want to have with your family."
Agholor caught a 62-yard touchdown pass and Tre Madden had a 63-yard TD catch in the first quarter for the Trojans, who had the Coliseum rocking as they roared to a 25-point lead in the first half.
After Garic Wharton caught his second TD pass for Arizona with 4:18 to play, Silas Redd punctuated his season debut for USC with seven consecutive clock-draining runs for 43 yards in a drive that began at the Trojans' 4, allowing USC to ensure a sideline shower for Orgeron.
"These men have been fantastic," Orgeron said. "We really have a close bond here."
Nearly 12 days after Kiffin's stormy four-year tenure ended in a dark airport parking lot, the Trojans played with passion and excitement for Orgeron, who promised to return fun to a season dominated by drudgery. The Coliseum crowd that booed frequently last month amid chants of "Fire Kiffin!" gave several standing ovations to the Trojans in a rare Thursday night game at the historic stadium.
Clay Helton, the Trojans' new playcaller in Kiffin's absence, dialed up an aggressive game plan that succeeded even without star receiver Marqise Lee, who sat out with a sprained knee. Justin Davis also rushed for a score for the Trojans, who racked up 546 total yards.
Orgeron's first game brought a new vibe to the Coliseum, which loved the coach's enthusiasm and passion for USC. Six fans in the front row of the student section painted "COACH O" on their bare chests -- a fitting tribute to a coach who was known to rip off his own shirt to fire up his players in his Ole Miss days.
"I think Coach O really brought something special to us," said right tackle Kevin Graf, who was recruited by Orgeron's former boss, Pete Carroll. "Coach O really brought Coach Carroll back. That meant a lot to me."
B.J. Denker passed for 363 yards and four touchdowns for the Wildcats (3-2, 0-2) in their second straight loss.
Ka'Deem Carey rushed for 138 yards in his eighth straight 100-yard game for Arizona, while Nate Phillips and David Richards also caught touchdown passes. Once the Wildcats recovered from the USC offense's biggest plays early on, they controlled much of the second half.
"We waited too late to get going," Arizona linebacker Marquis Flowers said. "We waited too long to try to execute, and we ran out of time. We made mistakes, and they saw the mistakes we made."
Although USC had just two healthy scholarship receivers, Helton regularly called long, daring pass plays -- something the notoriously conservative Kiffin rarely tried. USC managed just one pass play longer than 60 yards under Kiffin this season, but the Trojans had two TD catches longer than that in the first 10 minutes against the Wildcats.
Kessler threw a long pass down the middle on the Trojans' first play of their second series. Agholor, the speedy sophomore who replaced Robert Woods in this season's starting lineup, sprinted to make a fingertip catch just 3:39 in, stunning a crowd starved for exciting football.
Madden caught a midrange pass over the middle a few minutes later and romped through the Arizona secondary.
Davis scored from 11 yards out in the second quarter before Allen made a high dive into the end zone for a 28-3 lead. Phillips slipped behind USC's defense for a 57-yard touchdown catch 56 seconds before halftime.
Richards caught a 9-yard TD pass with 6:48 to play, and Wharton pulled the Wildcats within seven points before Redd ran out the clock with a 10-yard run on third-and-8 with 1:38 left. Redd, the Penn State transfer who led USC in rushing last season, had 80 yards on the ground after missing the first five games of this season with a persistent knee injury.
Arizona linebacker Scooby Wright's left knee injury is not season-ending, according to an MRI Wright had after Thursday night's opening win over UTSA, sources told ESPN's Brett McMurphy.
Syracuse starting quarterback Terrel Hunt has a significant injury to his right Achilles, head coach Scott Shafer said after the Orange's season-opening 47-0 rout of Rhode Island.
The Mountain West told ESPN's Brett McMurphy that officials correctly ruled the final play that kept Colorado from getting a potential game-tying touchdown against Hawaii before time expired.
ESPN 300 running back Elijah Holyfield, the son of former heavyweight boxing champion Evander Holyfield, has decided to stay home and attend Georgia, he announced Friday.
Miami reserve linebacker Al-Quadin Muhammad has been suspended for the season opener against Bethune-Cookman on Saturday for a violation of team rules, a source confirmed to ESPN.com
Ohio State quarterback Cardale Jones is "doing fine" after he was released from the hospital Wednesday night after being treated for symptoms related to a migraine headache.