Vince Davidson rushed for 103 yards and a touchdown on 17 carries as the Bobcats (5-3, 4-1 Mid-American Conference) had scoring drives of 87, 47, 48, 85 and 26 yards.
Ohio's defense intercepted four passes, recovered two fumbles and sacked Miami quarterback Zac Dysert five times. The RedHawks (4-4, 3-1) were held to 11 yards rushing on 21 attempts.
Davidson scored on a 56-yard run, Harden scored on 3- and 48-yard runs, and Jackson scored on 1- and 2-yard runs as the Bobcats rushed for 222 yards.
Harden rushed for 62 yards on seven carries, and Jackson had 31 yards on 12 carries. Jackson also completed 10 of 19 passes for 149 yards.
Dysert completed 21 of 36 passes for 332 yards and two touchdowns.