San Diego (6-1, 4-0 Pioneer League) went ahead 24-17 on Mills' 3-yard pass to Brandon White with 9:09 left in the game before Hoekstra's punt return at the 7:42 mark.
Drake (5-2, 3-1) got close on Trey Morse's 2-yard touchdown run with 3:48 remaining, but after the kickoff the Toreros ran out all but the final 34 seconds.
Mills completed 26 of 36 passes for 306 yards and hit Sam Scudellari for TD passes of 2 and 6 yards.
Drake's Mike Piatkowski was 21 of 37 for 296 yards and threw an 18-yard touchdown pass to Joey Orlando midway through the third quarter. The Bulldogs tied the score at 17 on Jacob Schmudlach's 2-yard run less than four minutes into the fourth quarter.
Western Kentucky commit Jared Nash launches this snap from the bleachers and successfully sinks it in the garbage can.
Florida State coach Jimbo Fisher hopes quarterback Sean Maguire is ready to go full speed by the middle of June.
Graduate transfer quarterback Davis Webb has officially joined California, giving the Golden Bears an experienced option to replace No. 1 overall NFL draft pick Jared Goff.
First-year football coach Dino Babers, hired by former Syracuse AD Mark Coyle, is on the committee that will search for Coyle's replacement.
Hugh Freeze has some major holes to fill on offense with the departures of Laremy Tunsil and Laquon Treadwell, but there is Chady Kelly and good depth.
After transferring in from Montana State, Dakota Prukop has a checklist he's working from as he prepares to compete for the Oregon job.