"He's got some soreness and tenderness in that area that we're concerned with," Johnson said. "The doctor is gonna take a look at him tonight. But he's definitely out tonight and you can count him out for the next game."
James had surgery on Dec. 13 to repair a broken fifth metatarsal by inserting a screw in his right foot. He missed eight weeks before returning to the lineup on Feb. 25.
"It's been hurting a little bit," James said. "I still can play, but [trainer] Tim Walsh is just looking out for what's best for me. He told me, 'You're too young.' So we don't want to mess it up even more. He's just holding me out until it goes away and it's completely healed. It's tough, but I gotta do what's best for me.
"It's like 95 percent healed. I just got about five percent to go. On certain cuts I feel it, but it's nothing serious."
James, a rookie who was selected by the Nets in the first round of the 2010 NBA draft, has appeared in just 25 games this season, averaging 4.4 points and 3.4 rebounds. He also missed three games recently after sustaining a concussion while the Nets were playing the Toronto Raptors in London.
Johnson also said that the team will continue the same course of action with point guard Deron Williams (strained flexor tendon in right wrist). Williams, who sat out Sunday's loss to the Washington Wizards, will also miss Monday and Wednesday's games before being reevaluated prior to Friday night's matchup against the Orlando Magic.
"We'll see where we are after the three games," Johnson said.
Johnson also announced that guard Ben Uzoh would be recalled from the NBA Development League on Wednesday. Uzoh could provide minutes to short-term starter Jordan Farmar and Sundiata Gaines with Williams out.
Gaines was signed to a multiyear contract, which will be fully guaranteed for the 2011-12 season, on Sunday.
"He's played really well for us," Johnson said. "He's shot the ball really well and given us a spark off the bench."
Mike Mazzeo is a regular contributor to ESPNNewYork.com.