The surgery will be performed by Dr. David Porter at Indiana Heath Hospital in Indianapolis and involve the replacement of a screw in James' fifth metatarsal, which he fractured last season. James originally underwent surgery on his right foot on Dec. 13, 2010, and missed 33 games as a result.
The 24-year-old started the first seven games of this season before re-injuring his right foot in Boston on Jan. 4. The team originally characterized it as soreness, but an MRI taken later revealed that it was much worse than previously thought.
James had been averaging 4.9 points and 4.7 rebounds per game. Veteran DeShawn Stevenson has been starting in his absence, and the onus also will fall on sharpshooter Anthony Morrow to pick up the slack as well.
Small forward Shawne Williams (shin splints) came through Saturday's morning shootaround well, and could play Sunday night against Charlotte, coach Avery Johnson said. Williams has missed the last three games.
Mike Mazzeo is a regular contributor to ESPNNewYork.com.