Mario Manningham inactive for 49ers

Updated: October 18, 2012, 7:54 PM ET
Associated Press

SAN FRANCISCO -- Wide receiver Mario Manningham is among the inactives with a shoulder injury for the San Francisco 49ers against the Seattle Seahawks on Thursday night.

Brandon Jacobs is taking Manningham's spot on the active roster for the first time after a left knee injury sidelined the former New York Giants running back since the preseason.

Left tackle Joe Staley, who had a concussion in Sunday's 26-3 home loss to the Giants, has been cleared to play and is in San Francisco's ...

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