"He's very sore right now," coach Brad Childress said Sunday after a 20-16 win.
Tarvaris Jackson replaced him and helped Minnesota score a go-ahead touchdown in the third quarter.
"It feels good to go out there and have a team win," he said. "It was good to get out there and play.
"I just try and prepare week in, week out. You got to be ready any time."
Jackson was 8-of-10 for 105 yards with a touchdown, finishing with a career-best 143.8 passer rating.
"He did a good job coming in moving the football around and converting third downs," Childress said. "He knew exactly what he was doing."
In Jackson's first two starts, he barely completed half of his passes, threw one TD, one interception and averaged about 150 yards passing.
Frerotte was 7-of-10 for 70 yards with two interceptions against the Lions. He helped the Vikings win seven of 10 games and move atop the NFC North.