Detroit coach Rod Marinelli said the team would wait for results of the exam before exploring other options for a starting quarterback.
After Culpepper was hurt Sunday, Drew Henson was sacked on the final play.
Dan Orlovsky hopes to be healthy enough to play this week after being out for a month with a wrist injury. Drew Stanton has been sidelined for two weeks with a concussion, but is expected to be ready to play, if necessary.
The Lions (0-13) will close at Indianapolis, against New Orleans and at Green Bay, hoping to avoid being the NFL's first 0-16 team.