Roethlisberger, who currently has a five-game winning streak against Baltimore and is 7-2 against the Ravens in his career, missed the team's first meeting of the year due to a suspension. The quarterback said during the week that he will not miss this game.
Baltimore (8-3) won the first meeting with the Steelers (8-3) and this rematch has first place in the AFC North on the line as well as playoff seeding.
In other injury news, starting fullback Le'Ron McClain (ankle) did not play for the Ravens. Left tackle Michael Oher (knee) and safety Dawan Landry (concussion) were active for Baltimore. All three players were listed as questionable this week.
James Walker covers the AFC North for ESPN.com. Information from The Associated Press contributed to this report.