Here are the highlights and lowlights from games played Sunday.
Quarterback, Kansas City Chiefs
Wide receiver, Kansas City Chiefs
Running back, Kansas City Chiefs
Cassel outwitted his former mentor at USC, Seahawks coach Pete Carroll, throwing four TD passes in the Chiefs' rout. Three of his scoring passes went to Bowe, who caught 13 passes overall for 170 yards. Bowe has caught a TD pass in seven straight games. Charles ran for 173 yards on 22 carries and had a TD as the Chiefs routed host Seattle 42-24.
Quarterback, Green Bay Packers
Rodgers not only threw for 344 yards and one score, but he led the Packers in rushing (51 yards) and added another touchdown on the ground. Alas, it was not enough to upend the host Atlanta Falcons, who won 20-17.
Quarterback, St. Louis Rams
The rookie recorded his first 300-yard passing game and tossed three touchdown passes to pace the Rams' victory at Denver. Bradford was 22-of-37 for 308 yards passing and no interceptions in his first road win as a pro. The Rams won 36-33.
In recording a 20-0 shutout, one of the league's worst defenses limited the Titans' attack to 162 total yards. Chris Johnson, the league's third-leading rusher entering the game, was held to 5 yards on 7 carries. Houston DB Glover Quin had three interceptions.
Running back, Houston Texans
Foster rushed for 143 yards on 30 carries and added nine receptions for 75 yards.
Running back, Cleveland Browns
Hillis ripped through the Carolina Panthers for 131 yards and three scores. He added six receptions for 63 yards in the Browns' 24-23 victory.
Running back, Pittsburgh Steelers
Mendenhall had not rushed for 100 yards in a game since Week 3 at Tampa Bay. Sunday, he churned through the Buffalo Bills' defense for 151 yards. The Steelers beat the Bills 19-16 in overtime.
Kicker, Pittsburgh Steelers
Signed on Nov. 16 to replace the released Jeff Reed, Suisham calmly converted all four of his field goal attempts against the host Bills. His 41-yard field goal with 2:14 left in overtime beat the Bills.
In the Chargers' 36-14 road rout of the Colts, the defense intercepted Peyton Manning four times, returning two for scores. Kevin Burnett returned Manning's first pick 29 yards for a score. Eric Weddle matched that with a 41-yard return in the third quarter that broke open the game. And the Chargers shut out Indy for the final 30 minutes.
Quarterback, Indianapolis Colts
The Chargers picked off Manning four times, returning two for scores, in a 36-14 win Sunday that handed Indianapolis its most lopsided home loss since the four-time MVP has been the team's starting quarterback. Manning finished 31 of 48 for 285 yards with two TDs and has thrown seven interceptions in the last two weeks -- the most over any two-week span in his 13-year NFL career.
Wide receiver, Buffalo Bills
Coming off an 8-catch, 137-yard, 3-TD game against the Bengals in Week 11, Johnson had a Sunday to forget against the Steelers. He caught seven passes, but for just 68 yards. Unofficially, he had five drops -- including a potential 40-yard game winner in the end zone in OT.
Running back, Tennessee Titans
Against the normally porous Houston defense, Johnson rushed for 5 yards on 7 attempts. He had a long gain of 9 yards. Rookie QB Rusty Smith's NFL starting debut was also rough -- he finished with a 26.7 passer rating -- putting the pressure on CJ to perform.
Running back, Oakland Raiders
In a 33-17 home loss to the Dolphins, McFadden managed just 2 yards on 8 carries. He had four 100-yard rushing games in his first six outings this season.
Kicker, Carolina Panthers
The 20-year veteran converted three FGs against the Cleveland Browns, but he also missed two. His 42-yard FG attempt grazed the left upright and failed as time expired in the Browns' 24-23 victory.