Though Spiller (ankle) was unable to practice Tuesday, a decision on his availability for Thursday's game against the Brown will likely come down to game time, ESPN.com reports.

about 11 hours ago | Data Provided By

Edwards: Grading the new coaches

ESPN Insider Herm Edwards grades the NFL coaches who took over new teams this season through Week 4. Andy Reid and Marc Trestman lead the pack.

Source: Bills' Spiller to play Thursday night

Despite a sprained ankle, Buffalo Bills running back C.J. Spiller will play Thursday night against the Cleveland Browns, a league source said.

Harris: Week 4 Instant Impressions

Christopher Harris reviews Week 4's action, including big weeks from Adrian Peterson and Arian Foster.

Bills RB Spiller, Jackson both injured vs. Ravens

Buffalo Bills running back C.J. Spiller suffered an ankle injury in Sunday's win over the Baltimore Ravens and is uncertain of his status for next Thursday night's game against the Cleveland Browns.

Spiller was able to return to Sunday's game against the Ravens after leaving for a spell with an ankle injury.

about 2 days ago | Data Provided By

Fantasy Football Now: Friday

Cary Chow, Christopher Harris and Stephania Bell preview Week 4 and discuss what to expect from Rob Gronkowski.

Hard Count: RBs in focus, defensive metrics

Christopher Harris reviews some top issues for Week 4, including C.J. Spiller, Gio Bernard, Jacquizz Rodgers, top cornerbacks and new defensive metrics.

Clayton on Peyton, Aldon Smith and RG III

ESPN NFL Insider John Clayton comments on Peyton Manning's style of play, how the 49ers will deal with Aldon Smith's absence, the injuries to Ray Rice, Reggie Bush and C.J. Spiller, Robert Griffin III's future and more.

Bills RB Spiller expects to play vs. Ravens

C.J. Spiller has a thigh injury that is not considered serious, and the Buffalo Bills running back is expected to play in next weekend's game against the Baltimore Ravens.

Harris: Instant Impressions -- Week 3

Christopher Harris looks at Week 3's notable performers, including the Browns passing game taking off, backup running backs doing just fine and the eventual emergence of Tom Brady.

Bills RB Spiller exits game with knee injury

Buffalo Bills star running back C.J. Spiller suffered a knee injury in Sunday's game against the New York Jets and will not return.