2012 Regular Season NFL Leaders
| RK | PLAYER | PASS EPA | RUN EPA | SACK EPA | PEN EPA | TOTAL EPA | ACT PLAYS | QB PAR | QB PAA | TOTAL QBR |
| 1 | Ben Roethlisberger, PIT | 88.8 | 5.3 | -29.0 | 4.3 | 69.4 | 537 | 65.8 | 21.2 | 62.8 |
| 2 | Russell Wilson, SEA | 86.4 | 23.1 | -27.4 | 6.2 | 88.2 | 588 | 85.6 | 36.8 | 69.6 |
| 3 | Tony Romo, DAL | 120.4 | 1.2 | -31.1 | 1.1 | 91.5 | 779 | 95.3 | 30.7 | 62.7 |
| 4 | Matt Ryan, ATL | 122.2 | 12.1 | -25.4 | 5.5 | 114.4 | 717 | 117.6 | 58.1 | 74.5 |
| 5 | Joe Flacco, BAL | 62.7 | -2.3 | -29.6 | 8.9 | 39.7 | 664 | 48.8 | -6.4 | 46.8 |
| Andy Dalton, CIN | 65.8 | 13.7 | -34.7 | 3.6 | 48.5 | 667 | 56.8 | 1.5 | 50.7 | |
| 7 | Brandon Weeden, CLE | 18.9 | -4.5 | -22.5 | 0.1 | -8.0 | 624 | 4.0 | -47.8 | 26.6 |
| Sam Bradford, STL | 76.6 | 5.1 | -27.0 | -3.4 | 51.3 | 685 | 60.1 | 3.2 | 51.6 | |
| 9 | Matthew Stafford, DET | 90.5 | 5.2 | -21.1 | 7.8 | 82.4 | 846 | 93.3 | 23.1 | 58.9 |
| Nick Foles, PHI | 26.9 | 3.2 | -14.3 | 1.8 | 17.7 | 332 | 22.9 | -4.7 | 45.3 | |
| RK | PLAYER | PASS EPA | RUN EPA | SACK EPA | PEN EPA | TOTAL EPA | ACT PLAYS | QB PAR | QB PAA | TOTAL QBR |
| 11 | Michael Vick, PHI | 36.4 | 3.0 | -20.9 | 7.5 | 25.9 | 473 | 33.6 | -5.7 | 46.0 |
| 12 | Andrew Luck, IND | 73.4 | 21.1 | -24.4 | 19.3 | 89.5 | 778 | 100.9 | 36.3 | 65.0 |
| Cam Newton, CAR | 51.0 | 27.1 | -26.7 | 4.4 | 55.8 | 698 | 66.9 | 9.0 | 54.2 | |
| Ryan Tannehill, MIA | 55.0 | 4.5 | -24.2 | 10.8 | 46.2 | 624 | 56.1 | 4.3 | 52.3 | |
| 15 | Aaron Rodgers, GB | 108.9 | 19.1 | -39.0 | 13.8 | 102.9 | 726 | 113.4 | 53.2 | 72.5 |
| 16 | Robert Griffin III, WSH | 80.2 | 12.7 | -20.3 | 7.4 | 80.1 | 589 | 89.6 | 40.8 | 71.4 |
| 17 | Josh Freeman, TB | 65.1 | 2.8 | -21.4 | 3.6 | 50.2 | 681 | 63.0 | 6.5 | 53.1 |
| 18 | Blaine Gabbert, JAC | 24.4 | -0.4 | -15.5 | 4.6 | 13.1 | 359 | 19.9 | -9.9 | 40.9 |
| 19 | Chad Henne, JAC | 23.2 | -6.8 | -18.6 | 2.3 | 0.1 | 388 | 7.2 | -25.0 | 29.9 |
| Philip Rivers, SD | 49.2 | 0.1 | -31.9 | 5.7 | 23.1 | 661 | 35.8 | -19.0 | 40.6 | |
| RK | PLAYER | PASS EPA | RUN EPA | SACK EPA | PEN EPA | TOTAL EPA | ACT PLAYS | QB PAR | QB PAA | TOTAL QBR |
| Mark Sanchez, NYJ | 19.2 | -5.5 | -32.3 | 4.9 | -13.7 | 559 | -3.8 | -50.2 | 23.4 | |
| 22 | Eli Manning, NYG | 74.0 | 1.2 | -12.2 | 8.4 | 71.5 | 628 | 86.6 | 34.5 | 67.4 |
| 23 | Tom Brady, NE | 114.3 | 3.1 | -16.6 | 8.3 | 109.2 | 739 | 129.0 | 67.6 | 77.1 |
| Brady Quinn, KC | 5.9 | 0.4 | -11.4 | 2.8 | -2.3 | 269 | 2.5 | -19.8 | 27.4 | |
| Colin Kaepernick, SF | 45.5 | 15.2 | -11.8 | -2.5 | 46.4 | 316 | 54.8 | 28.5 | 76.8 | |
| 26 | Drew Brees, NO | 108.0 | -0.1 | -20.0 | -1.4 | 86.4 | 761 | 106.1 | 42.9 | 67.9 |
| Carson Palmer, OAK | 41.9 | -0.0 | -20.0 | 8.4 | 30.3 | 667 | 44.7 | -10.6 | 44.7 | |
| Jay Cutler, CHI | 39.9 | 16.4 | -23.3 | 4.0 | 37.0 | 559 | 49.6 | 3.2 | 51.9 | |
| 29 | Matt Schaub, HOU | 78.6 | -1.2 | -21.3 | 5.0 | 61.1 | 637 | 77.6 | 24.7 | 62.6 |
| Ryan Fitzpatrick, BUF | 43.3 | 2.2 | -18.8 | 3.3 | 30.0 | 626 | 43.9 | -8.0 | 45.8 | |
| RK | PLAYER | PASS EPA | RUN EPA | SACK EPA | PEN EPA | TOTAL EPA | ACT PLAYS | QB PAR | QB PAA | TOTAL QBR |
| 31 | Matt Hasselbeck, TEN | 23.5 | 0.2 | -9.6 | 0.5 | 14.6 | 266 | 20.8 | -1.2 | 48.5 |
| Jake Locker, TEN | 21.4 | 12.8 | -13.7 | 2.2 | 22.6 | 420 | 32.4 | -2.4 | 48.1 | |
| 33 | Alex Smith, SF | 41.7 | 3.7 | -13.4 | 2.5 | 34.5 | 295 | 43.5 | 19.0 | 70.1 |
| 34 | Matt Cassel, KC | 14.1 | 4.0 | -13.0 | 2.0 | 7.1 | 345 | 14.2 | -14.4 | 36.5 |
| 35 | Peyton Manning, DEN | 116.6 | 1.4 | -14.1 | 12.9 | 116.8 | 691 | 144.4 | 87.0 | 84.1 |
| 36 | Christian Ponder, MIN | 44.2 | 7.9 | -21.2 | 8.0 | 38.9 | 611 | 57.7 | 7.0 | 53.8 |
