2012 Regular Season NFL Leaders
| RK | PLAYER | RESULT | PASS EPA | RUN EPA | SACK EPA | PEN EPA | TOTAL EPA | ACT PLAYS | QB PAR | QB PAA | TOTAL QBR |
| 1 | Eli Manning, NYG | W 42-7 vs PHI in Wk 17 | 5.1 | 0.0 | -0.3 | 1.1 | 6.0 | 27 | 13.4 | 11.1 | 99.6 |
| 2 | Russell Wilson, SEA | W 50-17 @ BUF in Wk 15 | 4.7 | 7.2 | -1.0 | -0.1 | 10.8 | 37 | 17.1 | 14.1 | 99.3 |
| 3 | Alex Smith, SF | W 45-3 vs BUF in Wk 5 | 9.1 | 2.1 | 0.0 | -0.2 | 11.0 | 34 | 15.3 | 12.5 | 99.2 |
| 4 | Peyton Manning, DEN | W 38-3 vs KC in Wk 17 | 9.1 | 0.0 | 0.0 | 0.0 | 9.1 | 33 | 13.5 | 10.8 | 98.7 |
| 5 | Tom Brady, NE | W 45-7 @ STL in Wk 8 | 8.4 | -0.0 | 0.0 | 1.7 | 10.1 | 41 | 16.1 | 12.7 | 98.4 |
| 6 | Russell Wilson, SEA | W 42-13 vs SF in Wk 16 | 4.0 | 0.7 | -0.1 | 0.0 | 4.6 | 30 | 10.9 | 8.4 | 97.6 |
| 7 | Robert Griffin III, WSH | W 38-26 vs MIN in Wk 6 | 4.5 | 7.8 | -0.4 | 0.1 | 12.0 | 38 | 13.8 | 10.6 | 97.6 |
| 8 | Brady Quinn, KC | W 27-21 vs CAR in Wk 13 | 13.4 | 0.3 | -0.6 | 1.1 | 14.2 | 32 | 11.5 | 8.9 | 97.6 |
| 9 | Matt Ryan, ATL | W 40-24 @ KC in Wk 1 | 12.5 | 4.9 | -1.1 | -0.5 | 15.7 | 36 | 13.0 | 10.0 | 97.5 |
| 10 | Colin Kaepernick, SF | W 32-7 vs CHI in Wk 11 | 6.2 | -0.3 | -0.3 | 0.1 | 5.8 | 28 | 10.2 | 7.9 | 97.5 |
| RK | PLAYER | RESULT | PASS EPA | RUN EPA | SACK EPA | PEN EPA | TOTAL EPA | ACT PLAYS | QB PAR | QB PAA | TOTAL QBR |
| 11 | Mark Sanchez, NYJ | W 48-28 vs BUF in Wk 1 | 5.9 | 0.0 | 0.0 | 0.5 | 6.5 | 30 | 10.5 | 8.0 | 97.1 |
| 12 | Cam Newton, CAR | W 30-20 vs ATL in Wk 14 | 5.6 | 4.7 | -0.3 | 0.1 | 10.1 | 46 | 15.9 | 12.1 | 97.0 |
| 13 | Christian Ponder, MIN | W 36-22 @ STL in Wk 15 | 1.5 | 5.3 | -0.9 | 0.3 | 6.1 | 29 | 9.9 | 7.5 | 96.9 |
| 14 | Matt Ryan, ATL | W 31-18 @ DET in Wk 16 | 9.6 | 2.6 | -0.6 | 0.1 | 11.6 | 37 | 12.6 | 9.5 | 96.7 |
| 15 | Tony Romo, DAL | W 38-33 vs PHI in Wk 13 | 14.2 | 1.3 | -1.8 | -0.5 | 13.3 | 34 | 11.5 | 8.7 | 96.7 |
| 16 | Tom Brady, NE | W 52-28 @ BUF in Wk 4 | 10.5 | 2.3 | -0.4 | 0.3 | 12.7 | 38 | 12.7 | 9.5 | 96.5 |
| 17 | Peyton Manning, DEN | W 34-14 vs NO in Wk 8 | 8.1 | -0.0 | 0.0 | 0.1 | 8.1 | 35 | 11.5 | 8.6 | 96.3 |
| 18 | Matt Ryan, ATL | W 34-0 vs NYG in Wk 15 | 4.8 | 0.0 | -0.2 | -0.1 | 4.5 | 31 | 10.1 | 7.6 | 96.2 |
| 19 | Eli Manning, NYG | W 26-3 @ SF in Wk 6 | 8.2 | -0.3 | 0.0 | 0.0 | 7.9 | 29 | 9.4 | 7.0 | 96.0 |
| 20 | Aaron Rodgers, GB | W 42-24 @ HOU in Wk 6 | 10.4 | 0.4 | -1.0 | 0.7 | 10.6 | 44 | 14.0 | 10.3 | 95.8 |
| RK | PLAYER | RESULT | PASS EPA | RUN EPA | SACK EPA | PEN EPA | TOTAL EPA | ACT PLAYS | QB PAR | QB PAA | TOTAL QBR |
| 21 | Andrew Luck, IND | W 23-20 vs MIN in Wk 2 | 11.3 | 1.1 | -1.1 | 1.1 | 12.4 | 42 | 13.4 | 9.9 | 95.7 |
| 22 | Matt Ryan, ATL | W 30-17 @ PHI in Wk 8 | 8.4 | -0.2 | -0.6 | 1.9 | 9.5 | 42 | 13.3 | 9.8 | 95.7 |
| 23 | Tom Brady, NE | W 42-14 vs HOU in Wk 14 | 5.2 | 0.3 | -0.4 | 1.1 | 6.2 | 41 | 12.9 | 9.5 | 95.6 |
| 24 | Drew Brees, NO | W 38-17 @ OAK in Wk 11 | 7.0 | 0.0 | 0.0 | -0.6 | 6.3 | 29 | 9.1 | 6.7 | 95.6 |
| 25 | Aaron Rodgers, GB | W 30-20 @ STL in Wk 7 | 14.4 | -0.4 | -1.7 | 0.2 | 12.5 | 44 | 13.7 | 10.1 | 95.5 |
| 26 | Drew Brees, NO | W 35-28 @ TB in Wk 7 | 11.9 | -0.5 | 0.0 | -0.1 | 11.3 | 39 | 12.1 | 8.9 | 95.3 |
| 27 | Eli Manning, NYG | W 41-27 vs CLE in Wk 5 | 8.7 | 0.0 | 0.0 | 1.5 | 10.3 | 41 | 12.7 | 9.3 | 95.2 |
| 28 | Joe Flacco, BAL | W 44-13 vs CIN in Wk 1 | 9.9 | -0.7 | -1.6 | 0.7 | 8.3 | 36 | 11.1 | 8.1 | 95.1 |
| 29 | Andy Dalton, CIN | W 31-13 vs NYG in Wk 10 | 5.8 | 0.0 | 0.0 | -0.1 | 5.8 | 31 | 9.4 | 6.9 | 94.8 |
| 30 | Peyton Manning, DEN | W 31-23 @ CIN in Wk 9 | 10.2 | 0.0 | 0.0 | 3.1 | 13.3 | 38 | 11.4 | 8.3 | 94.7 |
| RK | PLAYER | RESULT | PASS EPA | RUN EPA | SACK EPA | PEN EPA | TOTAL EPA | ACT PLAYS | QB PAR | QB PAA | TOTAL QBR |
| 31 | Christian Ponder, MIN | W 37-34 vs GB in Wk 17 | 11.6 | 0.1 | -0.6 | 0.6 | 11.6 | 36 | 10.7 | 7.8 | 94.6 |
| 32 | Philip Rivers, SD | W 31-13 vs KC in Wk 9 | 6.5 | 0.0 | -0.3 | -0.2 | 6.0 | 27 | 8.1 | 5.8 | 94.5 |
| 33 | Peyton Manning, DEN | W 31-19 vs PIT in Wk 1 | 13.1 | 0.9 | -1.7 | 0.5 | 12.8 | 32 | 9.5 | 6.9 | 94.4 |
| 34 | Joe Flacco, BAL | W 33-14 vs NYG in Wk 16 | 7.4 | -0.1 | 0.0 | 0.4 | 7.7 | 44 | 13.0 | 9.4 | 94.4 |
| 35 | Josh Freeman, TB | W 34-24 vs SD in Wk 10 | 8.1 | 0.6 | -0.6 | 0.0 | 8.1 | 22 | 6.5 | 4.7 | 94.4 |
| 36 | Tom Brady, NE | W 59-24 vs IND in Wk 11 | 9.3 | 0.0 | 0.0 | -0.2 | 9.1 | 36 | 10.4 | 7.5 | 93.9 |
| 37 | Robert Griffin III, WSH | W 40-32 @ NO in Wk 1 | 7.7 | 0.6 | -0.9 | 2.5 | 10.0 | 42 | 12.2 | 8.7 | 93.8 |
| 38 | Andrew Luck, IND | W 27-10 @ JAC in Wk 10 | 4.5 | 2.9 | -1.5 | 1.1 | 6.9 | 33 | 9.4 | 6.7 | 93.7 |
| Robert Griffin III, WSH | W 31-6 vs PHI in Wk 11 | 5.8 | 0.5 | -0.6 | -0.1 | 5.6 | 35 | 10.1 | 7.2 | 93.7 | |
| 40 | Russell Wilson, SEA | L 28-24 @ DET in Wk 8 | 11.8 | 1.2 | 0.0 | 2.1 | 15.1 | 40 | 11.5 | 8.1 | 93.7 |
| RK | PLAYER | RESULT | PASS EPA | RUN EPA | SACK EPA | PEN EPA | TOTAL EPA | ACT PLAYS | QB PAR | QB PAA | TOTAL QBR |
| 41 | Peyton Manning, DEN | W 34-12 vs CLE in Wk 16 | 9.7 | 0.0 | 0.0 | 0.5 | 10.1 | 55 | 15.6 | 11.1 | 93.6 |
| 42 | Ben Roethlisberger, PIT | W 27-10 vs NYJ in Wk 2 | 11.9 | 0.0 | -1.7 | -0.2 | 10.1 | 37 | 10.5 | 7.4 | 93.4 |
| 43 | Andy Dalton, CIN | W 38-31 @ WSH in Wk 3 | 11.5 | 1.8 | -1.8 | 0.2 | 11.7 | 34 | 9.6 | 6.8 | 93.4 |
| 44 | Joe Flacco, BAL | W 31-30 vs NE in Wk 3 | 10.7 | 1.0 | 0.0 | 4.2 | 15.9 | 50 | 14.1 | 9.9 | 93.2 |
| 45 | Jay Cutler, CHI | L 23-17 vs SEA in Wk 13 | 8.6 | 2.3 | 0.0 | 0.4 | 11.2 | 36 | 10.1 | 7.1 | 93.2 |
| 46 | Peyton Manning, DEN | W 26-13 @ OAK in Wk 14 | 9.9 | 0.0 | -2.1 | 2.5 | 10.4 | 46 | 12.9 | 9.1 | 93.1 |
| 47 | Eli Manning, NYG | W 36-7 @ CAR in Wk 3 | 7.3 | -0.4 | -0.2 | -0.1 | 6.6 | 39 | 10.9 | 7.7 | 93.1 |
| 48 | Matthew Stafford, DET | W 31-14 @ JAC in Wk 9 | 8.3 | 0.0 | -0.4 | 0.6 | 8.4 | 36 | 9.7 | 6.8 | 92.4 |
| 49 | Alex Smith, SF | W 24-3 @ ARI in Wk 8 | 7.9 | 0.0 | -1.6 | -0.2 | 6.1 | 29 | 7.8 | 5.3 | 92.0 |
| 50 | Peyton Manning, DEN | W 37-6 vs OAK in Wk 4 | 8.3 | 0.0 | 0.0 | -0.1 | 8.2 | 42 | 11.2 | 7.8 | 92.0 |
