Offensive Leaders
| QUARTERBACK RATING | RAT | |
Drew Brees | 1. Drew Brees, NO | 109.6 |
| 2. Brett Favre, MIN | 107.2 | |
| 3. Philip Rivers, SD | 104.4 | |
| 4. Aaron Rodgers, GNB | 103.2 | |
| 5. Ben Roethlisberger, PIT | 100.5 | |
| Complete Leaders | ||
| RUSHING YARDS | YDS | |
Chris Johnson | 1. Chris Johnson, TEN | 2006 |
| 2. Steven Jackson, STL | 1416 | |
| 3. Thomas Jones, NYJ | 1402 | |
| 4. Maurice Jones-Drew, JAC | 1391 | |
| 5. Adrian Peterson, MIN | 1383 | |
| Complete Leaders | ||
| RECEIVING YARDS | YDS | |
Andre Johnson | 1. Andre Johnson, HOU | 1569 |
| 2. Wes Welker, NE | 1348 | |
| 3. Miles Austin, DAL | 1320 | |
| 4. Sidney Rice, MIN | 1312 | |
| 5. Randy Moss, NE | 1264 | |
| Complete Leaders | ||
Defensive Leaders
| TACKLES | TACK | |
Patrick Willis | 1. Patrick Willis, SF | 152 |
| 2. London Fletcher, WAS | 142 | |
| 3. Barrett Ruud, TB | 142 | |
| 4. Jon Beason, CAR | 142 | |
| 5. Ray Lewis, BAL | 134 | |
| Complete Leaders | ||
| SACKS | SACK | |
Elvis Dumervil | 1. Elvis Dumervil, DEN | 17 |
| 2. Jared Allen, MIN | 14.5 | |
| 3. LaMarr Woodley, PIT | 13.5 | |
| 4. Dwight Freeney, IND | 13.5 | |
| 5. Will Smith, NO | 13 | |
| Complete Leaders | ||
| INTERCEPTIONS | INT | |
Darren Sharper | 1. Darren Sharper, NO | 9 |
| 2. Charles Woodson, GNB | 9 | |
| 3. Jairus Byrd, BUF | 9 | |
| 4. Asante Samuel, PHI | 9 | |
| 5. Darrelle Revis, NYJ | 6 | |
| Complete Leaders | ||
Data provided by Elias Sports Bureau
