Offensive Leaders
| QUARTERBACK RATING | RAT | |
Chad Pennington | 1. Chad Pennington, NYJ | 104.2 |
| 2. Rich Gannon, OAK | 97.3 | |
| 3. Brad Johnson, TB | 92.9 | |
| 4. Trent Green, KC | 92.6 | |
| 5. Peyton Manning, IND | 88.8 | |
| Complete Leaders | ||
| RUSHING YARDS | YDS | |
Ricky Williams | 1. Ricky Williams, MIA | 1853 |
| 2. LaDainian Tomlinson, SD | 1683 | |
| 3. Priest Holmes, KC | 1615 | |
| 4. Clinton Portis, DEN | 1508 | |
| 5. Travis Henry, BUF | 1438 | |
| Complete Leaders | ||
| RECEIVING YARDS | YDS | |
Marvin Harrison | 1. Marvin Harrison, IND | 1722 |
| 2. Randy Moss, MIN | 1347 | |
| 3. Amani Toomer, NYG | 1343 | |
| 4. Hines Ward, PIT | 1329 | |
| 5. Plaxico Burress, PIT | 1325 | |
| Complete Leaders | ||
Defensive Leaders
| TACKLES | TACK | |
Zach Thomas | 1. Zach Thomas, MIA | 156 |
| 2. Brian Urlacher, CHI | 151 | |
| 3. London Fletcher, BUF | 147 | |
| 4. Edgerton Hartwell, BAL | 142 | |
| 5. Jay Foreman, HOU | 141 | |
| Complete Leaders | ||
| SACKS | SACK | |
Jason Taylor | 1. Jason Taylor, MIA | 18.5 |
| 2. Simeon Rice, TB | 15.5 | |
| 3. Dwight Freeney, IND | 13 | |
| 4. Andre Carter, SF | 12.5 | |
| 5. Hugh Douglas, PHI | 12.5 | |
| Complete Leaders | ||
| INTERCEPTIONS | INT | |
Rod Woodson | 1. Rod Woodson, OAK | 8 |
| 2. Brian Kelly, TB | 8 | |
| 3. Darren Sharper, GNB | 7 | |
| 4. Tony Parrish, SF | 7 | |
| 5. Greg Wesley, KC | 6 | |
| Complete Leaders | ||
Data provided by Elias Sports Bureau