Earlier, Browns coach Mike Pettine would not name a starting quarterback for what he described as competitive reasons.
Pettine said Manziel took the majority of reps in Friday's practice and that Josh McCown was limited as he recovers from rib injuries. Pettine said earlier in the week that McCown would start if healthy.
Manziel started for an injured McCown in a 31-10 loss to the Cincinnati Bengals on Nov. 5. Manziel finished 15-of-33 for 168 yards and a touchdown, and after the game the second-year player said he "absolutely" wanted to remain the starter.