McFadden had two carries for 4 yards and caught one pass early before leaving the game Sunday. He returned to the sideline with his right foot taped.
McFadden was on crutches and had a walking boot Monday. Jackson said the plan was to rest McFadden this week anyway.
Linebacker Rolando McClain appeared to re-injure his sprained left ankle in the second quarter. He moved in and out of the lineup in the second half.
The Raiders also lost safety Matt Giordano to a neck injury.
Information from The Associated Press contributed to this report.