Ponder went 4 for 10 for 28 yards before aggravating a hip injury. Joe Webb, who rallied the Vikings to victory last week at Washington and brought them within 1 yard of the same at Detroit on Dec. 11, went 17 for 32 for 200 yards and two interceptions. He netted only 2 yards on 4 rushes.
The Bears defeated the Vikings 17-13.
The rookie was crunched by Bears defensive lineman Israel Idonije just after throwing an incomplete pass. Ponder was able to walk off under his own power, but he was limping badly and in noticeable pain.
Webb replaced Ponder for the third time in the last four games. Ponder was knocked out of last week's game with a concussion, but passed all the necessary tests this week to be cleared to play.
Ponder first injured his hip earlier this season against Denver, but did not miss a start because of it.
Information from The Associated Press was used in this report.