The St. Louis Rams fired both coach Steve Spagnuolo and general manager Billy Devaney, according to a team source.
Spagnuolo and Devaney reportedly were informed of their ousters Monday morning.
Spagnuolo was just 10-38 in three seasons in St. Louis.
The Rams lost 34-27 to the rival 49ers on Sunday to finish the season 2-14, tied with the Indianapolis Colts for the worst record in the NFL.
The lowly mark was an even bigger embarrassment considering it followed a six-win improvement last season. Attendance at Sunday's regular-season finale was announced as 55,990, about 9,000 shy of capacity at the Edward Jones Dome, but the stadium appeared no better than half-full and drained quickly in the second half.
Spagnuolo still talked optimistically about offseason plans after Sunday's loss and never fretted that this could have been his final game.
"I don't go there. I think you know me well enough," Spagnuolo said. "In the middle of that game, in the fourth quarter as exciting as it was? Nah."
Chris Mortensen is a senior NFL analyst for ESPN. Information from The Associated Press contributed to this report.