Source: Mike Iupati has MCL sprain
Get the latest NFL injury news
Who's out? Who's good to go? Who's questionable? We've got all the latest injury news from around the NFL. Injury Wire
Iupati was carted off to the locker room during the 49ers' 23-20 loss at New Orleans on Sunday. He was seen leaving the locker room on crutches and with his knee in a brace.
During the game, Iupati was replaced by Adam Snyder.
The 49ers' offense is struggling. It has not been able to cross the 200-total yard plateau in two straight games, and it had five three-and-outs Sunday.
Information from ESPN NFL Insider Adam Schefter and ESPN.com San Francisco 49ers reporter Bill Williamson contributed to this report.
MORE NFL HEADLINES
- Panthers officially cut ties with receiver Smith
- Sources: Pats' Wilfork asks team for release
- Eagles acquire Sproles for 5th-round pick
- Bengals release veteran linebacker Harrison