ScheduleAll times ET

2015 Schedule
2-2, 1st in NFC East
Field's most interesting storylines of Week 6 (2:49)
Mark J. Rebilas/USA TODAY Sports
11hOhm Youngmisuk

Cromartie calls Beckham a 'one-year wonder'

Jets cornerback Antonio Cromartie added fuel to the New York rivalry when he explained why he thinks Giants star wideout Odell Beckham Jr. is a "one-year wonder."

49ers TE Davis (knee) will not play vs. Giants (2:20)
Cromartie on O.B.J.: 'One-year wonder' (1:50)
ESPN Illustration

Giants are gaining support

After upsetting Buffalo in Week 4, New York's (-7) bandwagon is starting to fill up. Is Dave Tuley along for the ride against the 49ers? NFL best bets (Insider)

Mike Rodak ESPN Staff Writer 

The NFL has fined Bills DE Jerry Hughes for $23,152 for abusive language towards a game official and an additional $8,681 for head-butting a Giants player after a play in the Bills' 24-10 loss last Sunday.

Bill Kostroun/AP

Everything has changed

Last season the 49ers picked off Eli Manning five times in a 16-10 victory. So why won't San Francisco's defense wreak havoc on New York this time around? NFL Nation predictions

Two-way Whitlock symbolizes Giants' early overachievement (1:19)
Alex Goodlett/Getty Images

Jaworski: Eli getting rid of ball quickly

ESPN NFL analyst Ron Jaworski comments on Bill O'Brien's indecision at QB for the Texans, the deficiencies of Ryan Mallet, Eli Manning's improvement in facing the blitz and more.

AP Photo/Tony Gutierrez

Giants are thin at tight end

With Daniel Fells on injured reserve, watch for Larry Donnell's snaps to increase. Will the Giants' tight end be a reliable fantasy option moving forward? Fantasy advice (Insider)

McAdoo's offensive system thriving for Giants (1:31)
Better Week 5 flex play: Rueben Randle or Andre Ellington? (1:24)
49ers' Brooks out Sunday following sister's death (0:34)
How to bet on San Francisco-New York (N) (1:00)
Ed Mulholland/USA TODAY Sports

Is Eli Manning on the love list?

The Giants' quarterback should have no issue lighting up the 49ers this week. San Francisco has given up 340 passing yards a game and a total of five touchdown passes on the road this season. Berry: Love/Hate

AP Images/Jonathan Bachman
2dAdam Schefter

49ers' Brooks out Sunday following sister's death

San Francisco 49ers linebacker Ahmad Brooks will not play Sunday against the New York Giants after his 40-year-old sister, Casandra, died from lupus, his agent, Greg Williams, said.

Double Check: 49ers-Giants (1:00)

Ohm Youngmisuk ESPN Staff Writer 

Victor Cruz says he can feel a difference already from PRP to calf. He has to wait 10 days after PRP before he can even talk to doctors about what he can do next. But he he's convinced he will play this season and play at a high level again.

Start Eli Manning in Week 5 (1:32)

Team Stats

Passing Yards242.819th
Rushing Yards93.024th
Points For25.59th
Points Against20.511th

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