Alfredsson has been dealing with a back injury, and Detroit coach Mike Babcock said he "needed another day." He'd been a nonfactor in the first two games of the series, failing to register a goal, assist or shot on goal despite averaging 15:39 of ice time.
Babcock will insert center Joakim Andersson in Alfredsson's place in the lineup.
"Andersson can really help our penalty killing," Babcock said. "He's a good faceoff guy, he knows how to play."
Andersson gained valuable experience down the stretch last season, playing 14 playoff games for the Red Wings against the Anaheim Ducks and Chicago Blackhawks, putting up five points in the process.