The league-worst Blues will try to score a goal for the first time in their last three road games when they face the streaking Avalanche for the first time this season.
Colorado has won its last four games thanks to an improved defensive attitude and some solid goaltending. Rookie netminder Peter Budaj allowed only two goals in Saturday's victory over Phoenix and David Aebischer has yielded a total of four tallies over the last three contests.
In Saturday's 3-2 shootout triumph vs. Columbus, Aebischer made 19 saves - including one on a breakaway in overtime - and denied 3-of-4 attempts in the shootout.
Alex Tanguay and rookie sensation Marek Svatos scored first-period power-play goals and each added a tally in the shootout to lift the Avalanche to their fourth win in five home games.
Meanwhile, St. Louis has won a league-low 10 games and enters having dropped four of its last five.
The Blues are coming off their second straight shutout on the road - a 3-0 defeat at the hands of Detroit on Thursday. Curtis Sanford made 28 saves for St. Louis, which managed only 15 shots and went 0-for-4 with the man advantage.