After opening this trek with a loss, Skinner and the Hurricanes will try to bounce back and keep red-hot Taylor Hall in check Tuesday night against the Oilers.
Carolina (13-13-5) was shut out for the second time this season Monday, falling 2-0 at Vancouver in the opener of this trip.
The Hurricanes had won three in a row overall and on the road, scoring 14 goals during both streaks.
"I thought we were coming on," Carolina coach Kirk Muller said. "You have to fight for your opportunities, and in the second we got going, and the third we got a lot of juice but they are not giving up a lot of chances."
Skinner had a team-high five shots Monday, but was held without a point in back-to-back games after scoring five goals and assisting on another over the previous two.
Skinner leads the Hurricanes with nine goals, six coming in 11 road games.
He has two goals and two assists in two career meetings with the Oilers, scoring a power-play goal in a 5-3 win in his only visit to Edmonton on Dec. 7, 2011.
The Hurricanes have split six meetings with the Oilers since beating them in Game 7 of the 2006 Stanley Cup finals. However, they've won the last two matchups while scoring 12 goals.
The Oilers (10-18-3) sit at the bottom of the West standings, but are 6-3-1 since losing 10 of 11.
Hall has been a big part of the team's improved play, tallying six goals and six assists in his last nine games. His 25 points tie him with David Perron and Jordan Eberle for the team lead.
While Hall has been doing his part offensively, coach Dallas Eakins feels he's also having a strong impact defensively.
"Taylor Hall is always going to get his offense, he is," Eakins told the team's official website. "The place that Taylor is improving, not only from the eyes of the coaches but our people upstairs, is his defensive play.
"It's small, little things that we have been promoting with him and he's taken to heart and he's getting better at. He's turning into a much more rounded player and he's a horse. When he's on, he carries our team."
Hall has five goals with as many assists during a six-game point streak at home. He kept the streak going by scoring with 10.1 seconds left in regulation, but the Oilers fell 2-1 in overtime to Calgary on Saturday.
Hall was held without a point in a 7-1 road loss in his only meeting with the Hurricanes on Nov. 9, 2010, while Skinner had one goal and two assists.
Ryan Nugent-Hopkins had a goal in the most recent matchup with Carolina, but he enters this one with one point in four games. The center had eight over the previous five contests.
The Oilers likely will have to contend with Cam Ward in net after Justin Peters stopped 24 of 25 shots against the Canucks.
Ward has won the last two games against Edmonton while turning away 43 of 44 shots.
He's 3-1-1 with a 3.14 goals-against average in six road games.