Weber dropped to the ice at 15:24 of the second after being hit by a puck near his right eye. The defenseman got up and went immediately to the locker room. He did not return with what team officials called an upper-body injury.
He went into the game tied with Erik Karlsson of Ottawa, Torey Krug of Boston and Michael Stone of Phoenix for the most goals among NHL defensemen with seven. Weber is the only defenseman leading his team in goals.
"Obviously, if we lose our captain, it's always hard, and we hope he's OK and hopefully he gets back soon," Nashville defenseman Roman Josi said.