Fellow center Pavel Datsyuk remains out because of a concussion.
Zetterberg has 11 goals and 19 assists for a team-high 30 points, and Datsyuk has a team-high 12 goals and 11 assists. The Red Wings hope to know more about Datsyuk's status Wednesday. He was to be reevaluated Tuesday, but there's no timetable for his return.
The Red Wings host Philadelphia on Wednesday night.
Detroit recalled center Cory Emmerton from the AHL's Grand Rapids Griffins on Tuesday.