Kiprusoff, who left Tuesday's game after the second period, is listed as day to day.
"In the second period I felt some discomfort in the lower body area," Kiprusoff said in a statement. "During the intermission, it was decided that I not return to play. I really believe that this is a short-term injury and over the next days, I'll work toward being ready as soon as possible."
Backup Leland Irving stopped all six shots he faced in the third period against the Red Wings. Calgary (2-3-2) is last in the Western Conference with six points entering Wednesday.
Kiprusoff, who has played in all seven games this season, has a .870 save percentage and 3.24 goals-against average. He has played in more than 70 games in each of the past seven seasons for the Flames.
Taylor's deal is worth $525,000. He has spent the past two seasons with the American Hockey League's Abbotsford Heat.