The 'Nation missed just one of the 22 games involving Top 25 teams last week - Boston College's 34-33 upset of then-No. 18 Clemson - but three overwhelming favorites nearly tripped up. Florida State (97 percent), Tennessee (96 percent) and Iowa (95 percent) all won by a touchdown or less in games that came down to the wire.
SportsNation has its work cut out for itself this week, though, with seven games pitting ranked teams against each other including a pair in the SEC.
Which way will you lean in this week's top battles? Can LSU go into Jordan-Hare and knock off Auburn? Can Chris Leak and the Gators be able to hold off Tennessee? Will Michigan knock the Fighting Irish out of the No. 2 spot in the polls? Will Miami avoid a 1-2 start by getting to Brian Brohm and Louisville?
Scroll down the page, make your picks and check back at the end of the weekend to see how your picks stacked up.
SportsNation's 2006 Pick 'Em percentage: .933 (42-for-45)