Will the Chicago Bears be able to handle LaDainian Tomlinson and the San Diego Chargers? Will a Michael Vick-less Atlanta Falcons get off on the right foot against the Vikings. Will Randy Moss lead the Patriots to a win over the Jets? And don't forget the Monday Night Football doubleheader on ESPN.
Simply scroll down the page, make your picks and check back at the end of the weekend to see how SportsNation fared!