Updated: Oct 9, 2012, 6:41 PM

Vote: NFL Week 6 Pick 'Em

Peyton Manning Will the Giants defeat the 49ers for the second straight time?

How will the sixth week of the NFL season unfold?

In a rematch of last season's NFC Championship Game, the Giants travel west to face the 49ers. With former G-Men Brandon Jacobs and Mario Manningham now playing by the bay, are you confident San Francisco will get a win?

The last time the Cowboys faced the Ravens, Tony Romo threw two touchdowns and was intercepted twice by Baltimore cornerback Ed Reed in a 33-24 loss. How will
Dallas fare this time around?

Cast your votes below to see how your picks compare to SportsNation!

All games Sunday unless noted.

SportsNation's Week 5 record: 10-4

SportsNation's season record: 47-31


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