Maria Sharapova pulled out of the BNP Paribas Open on Thursday, citing a left forearm injury that has plagued her all season.
The world No. 7 hasn't played since losing to Serena Williams in the quarterfinals of the Australian Open in January.
"I am extremely disappointed that I am unable to compete in this year's BNP Paribas Open," Sharapova said in a statement to Indian Wells. "I have been focused on healing my left forearm injury and tried to get my body to be 100 percent ready to play this event, as it is one of my favorite events on the WTA and so close to my home in L.A. I know the tournament will be a great success this year, and I will be anxious to return next year and hopefully many years after."
Sharapova is a two-time champion in the desert of Indian Wells. She last won in 2013, sweeping all 12 of her sets en route to the title.
A five-time Grand Slam winner, Sharapova has been injury-ravaged for most of her career. Her forearm injury began late last season at the Wuhan Open, where she retired against Barbora Strycova in the third set and subsequently missed most of the Asian swing.
Sharapova joins Roger Federer on the sidelines for the first leg of the Indians Wells-Miami double.
Last week, Federer withdrew to continue his rehab from arthroscopic knee surgery.
Sharapova is still scheduled to play the Miami Open, which begins March 23.