Stanislas Wawrinka rallies for win
The second-seeded Frenchman broke twice in the opening set and three times in the second to close out a commanding performance on clay in 66 minutes.
Gasquet, who lost to Novak Djokovic in the 2007 Estoril final, hit 24 winners.
Need the scores from any match played in today's tournaments? Results
The big-serving Swiss saved break points in his first two service games before being broken in the sixth game on a double-fault. He broke back immediately and had five set points at one stage in the tiebreaker.
Wawrinka overpowered his opponent in the 20-minute second set, serving out the match in damp and windy conditions at the rain-disrupted event.
In the women's event, top-seeded Roberta Vinci advanced to the quarterfinals with a 6-2, 6-0 victory over Maria Joao Koheler.
Copyright 2012 by The Associated Press
MORE TENNIS HEADLINES
- Djokovic, Serena win ITF awards for 2013
- Former champ Becker to coach Djokovic
- Murray to return next week in Abu Dhabi
- Agent behind 'Decision' has hand in IMG deal