ROME -- Rafael Nadal began his bid for a seventh Rome title by cruising past local hope Fabio Fognini of Italy 6-1, 6-3 in just 61 minutes, and two-time defending champion Maria Sharapova eased past Spanish qualifier Garbine Muguruza 6-2, 6-2 at the Italian Open.
This tournament is a key clay-court warm-up for Roland Garros, the year's second Grand Slam, which starts on May 26.
Nadal will next face Latvian qualifier Ernests Gulbis, who reached the semifinals in 2010.
Gulbis routed Viktor Troicki of Serbia 6-1, 6-1. Early in the second set during an argument over a line call with the chair umpire, Troicki dragged a cameraman out onto the court to shoot the ball mark.
Stephens reached the Australian Open semifinals in January with a win over Serena Williams.
"She's been climbing up against the rankings," Sharapova said. "I haven't played against her in a while. I'm excited about that matchup."
Earlier, the 24th-ranked Janowicz improved his record against top-10 opponents to 3-5, having closed last year by reaching the Paris Masters final as a qualifier, beating Murray and Janko Tipsarevic along the way. The 22-year-old Janowicz is one of only five players under the age of 24 in the top 40.
After beating Tsonga with a forehand passing shot up the line on match point, Janowicz tore his shirt into pieces and tossed it to the crowd.
"I was really happy, especially because I didn't get off to a good start to the season and I was sick," said Janowicz, who has been bothered by ear, nose and throat infections. "Now I'm healthy."
In the women's tournament, last year's runner-up Li Na beat fellow Chinese player Zheng Jie 6-3, 6-1; seventh-seeded Sara Errani battled past Christina McHale of the United States 7-5, 5-7, 6-2; and 12th-seeded Maria Kirilenko eliminated Varvara Lepchenko of the United States 6-3, 6-1.
Also, 13th-seeded Roberta Vinci beat wild card and fellow Italian Nastassja Burnett 6-1, 6-4; 14th-seeded Dominika Cibulkova rallied past Melanie Oudin of the United States 5-7, 6-1, 6-3; and two-time champion Jelena Jankovic routed fellow Serb Bojana Jovanovski 6-2, 6-0.
Information from The Associated Press was used in this report.